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Article

Causal Relationship Between Gut Microbiota and Non-Suicidal Self-Injury: A Two-Sample Mendelian Randomization Study.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2025

Gao Jin, Pan Liangke, Wang Xinqi, Xu Jingjing, Xu Wangwang, Zhang Yang, Pan Zhenglun

Abstract excerpt

This study aims to determine the causal relationship between gut microbiota (GM) and Non-Suicidal Self-Injury (NSSI) using a two-sample Mendelian Randomization (MR) approach. By identifying Single Nucleotide Polymorphisms (SNPs) linked to both GM and NSSI, we explore bidirectional causal effects to uncover potential therapeutic pathways. A bidirectional MR analysis was conducted using GWAS data. SNPs associated...

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PMID: 40772736
DOI: 10.1002/ajmg.b.33050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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