Article
Screening and Verification COPD-OSA Overlap Syndrome Core Genes Using Bioinformatics.
International journal of chronic obstructive pulmonary disease - 1 Jan 2025
Qiang Shihao, Wan Rongrong, Wu Jingyi, Wang Chao, Cui Xiaochuan, Zhang Yunyun
Abstract excerpt
Background: When obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) coexist in a patient, it is called overlap syndrome (OS). However, the molecular mechanisms underpinning OS are unclear. To address this, we explored potential OS mechanisms using bioinformatics. Methods: OSA and COPD gene expression datasets were obtained from the Gene Expression Omnibus (GEO) database. Differential...
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