Identification of hub genes and key pathways in the emphysema phenotype of COPD

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition associated with high morbidity and mortality. This study aimed to use weighted gene co-expression network analysis (WGCNA) to explore the molecular pathogenesis of the emphysema phenotype of COPD. After obtaining lung mRNA expression profiles from ten patients with the emphysema phenotype of COPD and eight controls, emphysema-associated...

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• Biomarkers in Disease Mechanisms
• Chronic Obstructive Pulmonary Disease (COPD) Research
• IL-33, ST2, and ILC Pathways