Article
BTG1 Mutation Correlates with Inferior Prognosis in Diffuse Large B-Cell Lymphoma.
Cancer research and treatment - 1 Jul 2026
Shang Chun-Yu, Hua Wei, Xing Tong-Yao, Du Kai-Xin, Wu Yi-Fan, Li Yue, Yin Hua, Shen Hao-Rui, Wang Li, Li Jian-Yong, Gao Rui, Xu Wei, Liang Jin-Hua
Abstract excerpt
PURPOSE: B-cell translocation gene 1 (BTG1) is a highly conserved gene and recurrently mutated in the MCD subtype of diffuse large B-cell lymphoma (DLBCL). The specific enrichment of BTG1 mutation (BTG1mut) raises a potential hypothesis that they may actively contribute to DLBCL. However, the biological characteristics and prognostic signifi cance ofBTG1 in DLBCL remain to be explored. Therefore, the objective of...
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