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Estimating effects of serum vitamin B12 levels on psychiatric disorders and cognitive impairment: a Mendelian randomization study

30 Jul 2025

Abstract excerpt

BACKGROUND: Vitamin B12 deficiency can lead to pernicious anemia and has been associated with various neuropsychiatric diseases and cognitive decline. However, it is unclear whether increasing serum vitamin B12 levels can help to prevent the onset of psychiatric disorders and cognitive impairment in the general population. METHODS: Leveraging large-scale genome-wide association studies (GWASs), we conducted...

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PMID: 40739033
DOI: 10.1038/s43856-025-01043-x

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