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Circulating microRNA profiles in early-stage osteoarthritis and rheumatoid arthritis

29 Jul 2025

Abstract excerpt

Osteoarthritis (OA) and rheumatoid arthritis (RA) are prevalent joint diseases, yet early diagnosis remains challenging with existing methods. Circulating microRNAs are promising biomarkers for detection and differentiation of arthritis subtypes. This study aimed to profile plasma microRNAs from early OA (N = 22), early RA (N = 12), and non-OA/RA (N = 50) individuals using microRNA-sequencing. Principal component...

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PMID: 40730797
DOI: 10.1038/s41598-025-07922-6

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