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Article

Exploring the Genetic Landscape of Primary Marginal Zone Lymphoma of the Urinary Bladder.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2025

Balestri Ilaria, Ivanova Vanesa-Sindi, Gašljević Gorana, von Gunten Michael, Volavšek Metka, Hamelin Baptiste, Dirnhofer Stefan, Mertz Kirsten, Menter Thomas, Tzankov Alexandar

Abstract excerpt

Extranodal marginal zone B-cell lymphoma (MZL) of mucosa-associated lymphoid tissue is the most frequent primary lymphoma of the urinary bladder. Although MZLs from various anatomical sites are often associated with autoimmune disorders, infections, and site-characteristic genetic alterations, the molecular foundations and potential infectious triggers of urinary bladder MZL remain poorly understood. To elucidate...

Read the complete abstract on PubMed

Topics

Humans
Female
Male
Urinary Bladder Neoplasms
Aged
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Lymphoma, B-Cell, Marginal Zone

Aged, 80 and over

Biomarkers, Tumor

Adult

Mutation

Source

Identifiers

PMID: 40645588
DOI: 10.1016/j.modpat.2025.100838

Genes

TBL1XR1
BCL10
BCL2
BCL6
CD5
MALT1
MAP2K1
MYC
SOX11
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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