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Article

Liraglutide use in pediatric type 2 familial partial lipodystrophy caused by LMNA mutation: a case report.

BMC pediatrics - 7 Jul 2025

Li Youran, Yu Ronghua, Song Ting, Xiao Yongmei, Xu Wuhen, Zhang Ting, Li Xiaolu

Abstract excerpt

BACKGROUND: Type 2 familial partial lipodystrophy (FPLD2), or Dunnigan syndrome, is a rare genetic disorder characterized by selective subcutaneous fat loss, metabolic complications, and insulin resistance due to LMNA gene mutations. This case report describes the clinical presentation and treatment of a Chinese family with FPLD2, highlighting liraglutide's role in glycemic and lipid control. CASE PRESENTATION:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lipodystrophy, Familial Partial

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Source

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Identifiers

PMID: 40619352
DOI: 10.1186/s12887-025-05886-0
PMCID: PMC12232629

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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