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Article

PenCards: a global and community-contributed public archive of variant penetrance.

Journal of genetics and genomics = Yi chuan xue bao - 1 Feb 2026

Zhu Zhaopo, Shang Ling, Shao Chuhan, Wang Zheng, Mao Xinxin, Huang Yuanfeng, Yu Pei, Li Bin, Li Jinchen, Zhao Guihu

Abstract excerpt

Penetrance is a crucial indicator for accurately assessing disease risk and plays a vital role in disease research, gene therapy, and genetic counseling. However, with penetrance data dispersed across various sources, efficiently accessing and consolidating this information becomes a challenge. A comprehensive platform that integrates penetrance is urgently needed. Here, we present PenCards, a global,...

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Share to Databases, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 40619098
DOI: 10.1016/j.jgg.2025.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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