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Article

VarCards2: an integrated genetic and clinical database for ACMG-AMP variant-interpretation guidelines in the human whole genome.

Nucleic acids research - 5 Jan 2024

Wang Zheng, Zhao Guihu, Zhu Zhaopo, Wang Yijing, Xiang Xudong, Zhang Shiyu, Luo Tengfei, Zhou Qiao, Qiu Jian, Tang Beisha, Xia Kun, Li Bin, Li Jinchen

Abstract excerpt

VarCards, an online database, combines comprehensive variant- and gene-level annotation data to streamline genetic counselling for coding variants. Recognising the increasing clinical relevance of non-coding variations, there has been an accelerated development of bioinformatics tools dedicated to interpreting non-coding variations, including single-nucleotide variants and copy number variations. Regrettably,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37956311
DOI: 10.1093/nar/gkad1061
PMCID: PMC10767961

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