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Sperm metabolomic signatures of asthenozoospermia and teratozoospermia in Chinese reproductive-age men

4 Jul 2025

Abstract excerpt

Asthenozoospermia and teratozoospermia are common causes of male infertility. Despite their prevalence, the underlying metabolic mechanisms remain poorly understood. In this study, we conducted targeted metabolomic profiling of sperm samples from 131 Chinese reproductive-age men (48 normozoospermic controls, 40 asthenozoospermic patients, and 43 teratozoospermic patients) to identify distinct metabolic signatures...

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PMID: 40615526
DOI: 10.1038/s41598-025-09787-1

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