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Pre-conceptional paternal diet impacts on offspring testosterone homoeostasis via epigenetic modulation of cyp19a1/aromatase activity

17 Jun 2024

Abstract excerpt

Paternal eating habits, before and at conception, have a strong impact on offspring future metabolism. By sending specific epigenetic signals through spermatozoa, paternal nutrition influences developing embryos and increases offspring risk of developing dysmetabolism and cardiovascular diseases. Among the intergenerational consequences, paternal epigenetic messages affect embryo DNA methylation altering...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40604316
DOI: 10.1038/s44324-024-00011-8

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