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Article

Association of IgG4-related disease with human inborn errors of immunity.

Rheumatology (Oxford, England) - 1 Nov 2025

Batani Veronica, Benetti Elisa, Minici Claudia, Mahajne Jasmin, Segala Filippo, Lanzillotta Marco, Colavito Davide, Della-Torre Emanuel

Abstract excerpt

OBJECTIVES: IgG4-related disease (IgG4-RD) is considered a complex multifactorial condition because immunological, environmental and genetic factors contribute to its pathogenesis and protean clinical manifestations. While immunological and environmental factors have been extensively investigated, the contribution of genetic factors remains poorly understood. We sought to investigate a predisposing genetic...

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PMID: 40569058
DOI: 10.1093/rheumatology/keaf353

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LRBA
PRKDC

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