Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Progenitor Cell Dynamics in Androgenetic Alopecia: Insights from Spatially Resolved Transcriptomics

17 Jun 2025

Abstract excerpt

Androgenetic alopecia (AGA) is marked by the progressive miniaturization of hair follicles (HFs) and hair thinning, driven by a decline in the progenitor cells critical for hair regeneration. Despite this, the mechanisms responsible for progenitor cell depletion remain largely unclear. To investigate transcriptional alterations in the progenitor cell regions of AGA patients while maintaining the spatial tissue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hair Growth and Disorders
Share to Immune Cell Function and Interaction
Share to RNA regulation and disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40565255
DOI: 10.3390/ijms26125792

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Progenitor Cell Dynamics in Androgenetic Alopecia: Insights from Spatially Resolved TranscriptomicsPMID 40565255Read ↗

Disturbance of Immune Microenvironment in Androgenetic Alopecia through Spatial TranscriptomicsSemantic proximity Read ↗

Spatial transcriptome reveals disturbance of peri-infundibular immune infiltration in androgenetic alopeciaSemantic proximity Read ↗

Identification of Functional Patterns of Androgenetic Alopecia Using Transcriptome Profiling in Distinct Locations of Hair FolliclesSemantic proximity Read ↗

Single-cell transcriptomics reveals cellular hierarchies and aberrant CTS contraction-mediated premature hair regression in androgenetic alopeciaSemantic proximity Read ↗

Multimodal Human Scalp Atlas Defines Cell Landscape and Lineage Architecture In SituSemantic proximity Read ↗

Frontiers in the physiology of male pattern androgenetic alopecia: beyond the androgen horizonSemantic proximity Read ↗

A genomic approach to susceptibility and pathogenesis leads to identifying potential novel therapeutic targets in androgenetic alopecia.Semantic proximity Read ↗

The Biology and Genomics of Human Hair Follicles: A Focus on Androgenetic AlopeciaSemantic proximity Read ↗

Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathwaysSemantic proximity Read ↗

Comparative spatial transcriptomics of hair follicle-T cell interactions in mouse, dog and human reveals conserved drivers of primary cicatricial alopeciaSemantic proximity Read ↗

Single-Nucleus and Bulk RNA Sequencing Reveals the Involvement of Natural Killer and CD8+ T Cells in the Progression of Androgenetic AlopeciaSemantic proximity Read ↗

Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.