Article
BBSome: An essential component of hypothalamic regulation of energy homeostasis
25 Jun 2025
Abstract excerpt
The BBSome is a protein complex composed of eight Bardet-Biedl syndrome (BBS) proteins. Although the BBSome is best known for its role in regulating cilia function, accumulating evidence indicates that this protein complex is also involved in various cellular processes, including mitochondrial dynamics and receptor trafficking to the plasma membrane. BBSome deficiency is associated with a range of diseases,...
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