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On the origin of non-specific binders isolated in the selection of phage display peptide libraries

4 Jun 2025

Abstract excerpt

Over the recent decades, phage display has been used successfully to identify a variety of peptides with diagnostic and therapeutic applications. Despite the significant role of this technology in the pharmaceutical industry, the affinity selection of phage display peptide libraries through biopanning suffers from some limitations. The most significant drawback of phage display is the undesirable enrichment and...

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PMID: 40535010
DOI: 10.3389/fmicb.2025.1571679

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