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Article

Investigating the Impact of the Gut Microbiota on Nasal Polyp Development: Insights from Mendelian Randomization.

International archives of allergy and immunology - 1 Jan 2026

Lu Ning, Yao Yuxu, Gao Meiling, Liu Zhichen, Xie Huanxia, Liu Jisheng, Jiao Qingqing

Abstract excerpt

INTRODUCTION: Chronic rhinosinusitis with nasal polyps has a high post-surgery recurrence, suggesting complex pathology. However, research into underlying mechanisms and contributing factors, such as gut microbiota, is lacking. This study aimed to investigate the causal relationship between nasal polyps and gut microbiota, and to identify and quantify the potential mediating roles of metabolic pathways. We...

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PMID: 40532682
DOI: 10.1159/000546793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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