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Article

Hub Genes PRPF19 and PPIB: Molecular Pathways and Potential Biomarkers in COPD.

International journal of chronic obstructive pulmonary disease - 1 Jan 2025

Zhao Jiale, Ge Xiahui, Li Hailong, Jing Genfei, Ma Weirong, Fan Yuchun, Chen Juan, Zhao Zhijun, Hou Jia

Abstract excerpt

Background: Chronic Obstructive Pulmonary Disease (COPD), a complex respiratory disorder, results from genetic and environmental factors. Uncovering its genetic basis is vital for diagnostics and treatment. Robust genetic analysis is essential to establish a causal link. Methods: Genome-wide DNA methylation analysis was performed using the Illumina Infinium HumanMethylation850 BeadChip in peripheral blood from 8...

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Topics

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Share to Databases, Genetic
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Gene Regulatory Networks

Share to Mendelian Randomization Analysis

Share to Protein Interaction Maps

Share to Pulmonary Disease, Chronic Obstructive

Share to RNA-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 40524719
DOI: 10.2147/COPD.S511696
PMCID: PMC12168939

Genes

PPIB
PRPF19
DOHH
FKBP10
HSPA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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