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Fatty acid metabolism of granulose cells and follicular fluid and their associations with embryo quality in normal-weight women with PCOS

14 Jun 2025

Abstract excerpt

BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common reproductive-endocrine disorder in women of reproductive age. The granulosa cell metabolism correlated with oocyte competence. However, the alteration of fatty acid in granulosa cell of PCOS patients is unclear. Besides, obesity per se is related to dysfunction of oocyte quality. Hence, this study was aimed to comprehensively investigate the fatty...

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PMID: 40517267
DOI: 10.1186/s13048-025-01711-5

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