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Article

Idiopathic normal pressure hydrocephalus: A sulcal morphometry approach to brain phenotype and clinical response.

NeuroImage. Clinical - 1 Jan 2025

Miftari Arben, Pizzagalli Fabrizio, Bommarito Giulia, Armand Stéphane, Assal Frederic, Van De Ville Dimitri, Griffa Alessandra, Allali Gilles

Abstract excerpt

Idiopathic normal pressure hydrocephalus (iNPH), the leading cause of reversible dementia in older adults, is characterized by urinary incontinence, gait impairment, cognitive decline, and ventriculomegaly. Neuroradiological features rely on visual assessment, including sulcal characteristics. This study applies automatic sulcal-based morphometry to characterize the sulcal phenotype in iNPH and to distinguish...

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Identifiers

PMID: 40513356
DOI: 10.1016/j.nicl.2025.103816
PMCID: PMC12205340

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