Systematic proteomic and small RNA profiling of extracellular vesicles from cattle infected with a naturally occurring buparvaquone-resistant strain of Theileria annulata and from uninfected controls

Abstract excerpt

BACKGROUND: Extracellular vesicles (EVs) play a pivotal role in host-parasite interactions, particularly in facilitating parasite pathogenesis and immune modulation, and are crucial mediators of intercellular communication. Theileria annulata, an apicomplexan parasite, induces severe alterations in host cells, promoting uncontrolled proliferation, resistance to apoptosis, and immune evasion. Although EVs...

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