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Article

Characterization of a periodontal-inflammatory microRNA profile during multibracket orthodontic treatment in adolescents

3 Jun 2025

Abstract excerpt

This study aimed to identify functional microRNAs (miRNAs) and their respective targets as central regulatory factors of tooth movement during orthodontic treatment. Gingival crevicular fluid (GCF) of 24 adolescent patients (< 18 years) treated with a full-mouth multibracket appliance (MBA; Thermal Copper Nickel Titanium archwire) was analyzed for miRNAs-21, -29b, -34a, -126, -132, -146a, and -221. GCF samples...

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PMID: 40461544
DOI: 10.1038/s41598-025-01794-6

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