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Local cluster of gonorrhoea strains harbouring the Neisseria meningitidis porA gene: a re-emerging diagnostic escape mutant.

Sexually transmitted infections - 17 Feb 2026

Goldstein Emily, Ure Roisin, Winter Andrew, Currie Alison, McHugh Martin, Doumith Michel, Cole Michelle Jayne, Smith Andrew, Gunson Rory N

Abstract excerpt

OBJECTIVES: To investigate Neisseria gonorrhoeae specimens that exhibit diagnostic escape when the gonococcal porA pseudogene is employed as the target of nucleic-acid amplification tests (NAATs). METHODS: Eight NAAT specimens, from five patients, were identified as potential N. gonorrhoeae diagnostic escape mutants over a 7-month period (2023-2024) in Scotland. All specimens tested positive for N. gonorrhoeae on...

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PMID: 40441775
DOI: 10.1136/sextrans-2025-056520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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