Article
Domesticated cannabinoid synthases amid a wild mosaic cannabis pangenome.
Nature - 1 Jul 2025
Lynch Ryan C, Padgitt-Cobb Lillian K, Garfinkel Andrea R, Knaus Brian J, Hartwick Nolan T, Allsing Nicholas, Aylward Anthony, Bentz Philip C, Carey Sarah B, Mamerto Allen, Kitony Justine K, Colt Kelly, Murray Emily R, Duong Tiffany, Chen Heidi I, Trippe Aaron, Harkess Alex, Crawford Seth, Vining Kelly, Michael Todd P
Abstract excerpt
Cannabis sativa is a globally important seed oil, fibre and drug-producing plant species. However, a century of prohibition has severely restricted development of breeding and germplasm resources, leaving potential hemp-based nutritional and fibre applications unrealized. Here we present a cannabis pangenome, constructed with 181 new and 12 previously released genomes from a total of 144 biological samples...
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