Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In silico analysis enabling informed design for genome editing in medicinal cannabis; gene families and variant characterisation.

PloS one - 1 Jan 2021

Matchett-Oates L, Braich S, Spangenberg G C, Rochfort S, Cogan N O I

Abstract excerpt

BACKGROUND: Cannabis has been used worldwide for centuries for industrial, recreational and medicinal use, however, to date no successful attempts at editing genes involved in cannabinoid biosynthesis have been reported. This study proposes and develops an in silico best practices approach for the design and implementation of genome editing technologies in cannabis to target all genes involved in cannabinoid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cannabinoids
Share to Cannabis
Share to Clustered Regularly Interspaced Short Palindromic Repeats

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Gene Editing

Share to Genome, Plant

Share to RNA, Guide, CRISPR-Cas Systems

Share to User-Computer Interface

Source

Open in PubMed Open full text

Identifiers

PMID: 34551006
DOI: 10.1371/journal.pone.0257413
PMCID: PMC8457487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In silico analysis enabling informed design for genome editing in medicinal cannabis; gene families and variant characterisation.PMID 34551006Read ↗

Domesticated cannabinoid synthases amid a wild mosaic cannabis pangenome.Semantic proximity Read ↗

Hemp Genome Editing—Challenges and OpportunitiesSemantic proximity Read ↗

The draft genome and transcriptome of Cannabis sativa.Semantic proximity Read ↗

The genetics of Cannabis-genomic variations of key synthases and their effect on cannabinoid content.Semantic proximity Read ↗

Accumulation of somatic mutations leads to genetic mosaicism in CannabisSemantic proximity Read ↗

HASCH - A high-throughput amplicon-based SNP-platform for medicinal cannabis and industrial hemp genotyping applications.Semantic proximity Read ↗

Accumulation of somatic mutations leads to genetic mosaicism in cannabisSemantic proximity Read ↗

Whole-Genome Resequencing of Wild and Cultivated Cannabis Reveals the Genetic Structure and Adaptive Selection of Important TraitsSemantic proximity Read ↗

Machine learning-enhanced multi-trait genomic prediction for optimizing cannabinoid profiles in cannabis.Semantic proximity Read ↗

Somatic Mutation Accumulations in Micropropagated Cannabis Are Proportional to the Number of SubculturesSemantic proximity Read ↗

Genome editing technologies, mechanisms and improved production of therapeutic phytochemicals: Opportunities and prospectsSemantic proximity Read ↗

Whole-genome resequencing of wild and cultivated cannabis reveals the genetic structure and adaptive selection of important traits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.