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The characteristics of tissue microbiota in different anatomical locations and different tissue types of the colorectum in patients with colorectal cancer

27 May 2025

Abstract excerpt

ABSTRACT The gut microbiota is intricately associated with the onset and progression of colorectal cancer (CRC), leading to significant interest in developing prevention and treatment strategies that leverage gut microbiota. In this study, we collected 57 samples from 19 CRC patients, comprising cancerous tissue, paracancerous tissue, and normal mucosa. Utilizing metagenomic sequencing and bioinformatics...

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PMID: 40422085
DOI: 10.1128/msystems.00198-25

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