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Comparative pathogenicity of three A(H5N1) clade 2.3.4.4b HPAI viruses in blue-winged teal and transmission to domestic poultry.

mSphere - 25 Jun 2025

Alkie Tamiru N, Embury-Hyatt Carissa, Signore Anthony V, Baldwin Frank, Hisanaga Tamiko, Xu Wanhong, Moffat Estella, Giacinti Jolene A, Soos Catherine, Berhane Yohannes

Abstract excerpt

Long-distance migratory ducks play a critical role in the maintenance and dissemination of A(H5N1) viruses. Comparative pathogenicity studies were conducted on blue-winged teal (BWTE; Anas discors) using three distinct genotypes of A(H5N1) clade 2.3.4.4b viruses (A1, B1.3, and B4.1) isolated from wild ducks in Canada. Twenty-four hours post-intranasal infection of BWTE, contact turkeys and chickens were...

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Topics

Animals
Influenza in Birds
Chickens
Ducks
Influenza A Virus, H5N1 Subtype
Virulence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genotype

Turkeys

Poultry Diseases

Virus Shedding

Canada

Reassortant Viruses

Source

Open in PubMed Open full text

Identifiers

PMID: 40401902
DOI: 10.1128/msphere.00021-25
PMCID: PMC12188715

Genes

MALL
MB

Provenance

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