Article
The CarSR two-component system directly controls radD expression as a global regulator that senses bacterial coaggregation in Fusobacterium nucleatum
21 May 2025
Abstract excerpt
ABSTRACT Two-component systems (TCS) enable bacteria to sense and respond to environmental signals, facilitating rapid adaptation. Fusobacterium nucleatum , a key oral pathobiont, employs the CarSR TCS to modulate coaggregation with various gram-positive partners by regulating the expression of radD , encoding a surface adhesion protein, as revealed by RNA-Seq analysis. However, the direct regulation of the radD...
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