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Genetic and molecular determinants of polymicrobial interactions in Fusobacterium nucleatum

31 May 2021

Abstract excerpt

Significance Fusobacterium nucleatum interacts with many oral microbes and has the ability to spread to the placenta and amniotic fluid, promoting preterm birth. Yet, the molecular mechanisms underlying polymicrobial interactions, termed coaggregation, by Fusobacteria are poorly understood. Here, we revealed that the two-component signal transduction system CarRS regulates expression of genes encoding lysine...

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PMID: 34074747
DOI: 10.1073/pnas.2006482118

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