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Article

Well-Differentiated Adenocarcinoma With Papillary Architecture, Focal Residual Cilia, Apical Snouts, and CHEK2 and p53 Mutations.

Cytopathology : official journal of the British Society for Clinical Cytology - 1 Sept 2025

Gonzalez Maria F

Abstract excerpt

Ciliated adenocarcinomas are rare non-terminal respiratory unit-type lung adenocarcinomas characterised by ciliated cells with nuclear atypia and glandular or papillary architecture. A few cases of ciliated adenocarcinoma of the lung have been reported. These adenocarcinomas are negative for TTF1 and have either KRAS (25%) or EGFR (9%) mutations. A case of a well-differentiated adenocarcinoma with papillary...

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Identifiers

PMID: 40369890
DOI: 10.1111/cyt.13508

Genes

CHEK2
EGFR
KRAS
TTF1

Provenance

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