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Article

Ciliated Muconodular Papillary Tumors of the Lung Can Occur in Western Patients and Show Mutations in BRAF and AKT1.

The American journal of surgical pathology - 1 Dec 2016

Liu Liping, Aesif Scott W, Kipp Benjamin R, Voss Jesse S, Daniel Silver, Aubry Marie Christine, Boland Jennifer M

Abstract excerpt

Ciliated muconodular papillary tumors (CMPTs) are rare peripheral lung lesions, characterized by papillary architecture and ciliated columnar cells admixed with mucinous cells and basal cells. They often have prominent surrounding intra-alveolar mucin, which can lead to diagnostic confusion with mucinous adenocarcinoma. Recognition of the ciliated component is the key to diagnosis of CMPT. The literature contains...

Topics

Aged
Aged, 80 and over
Biomarkers, Tumor
Female
Humans
Lung Neoplasms
Male
Mutation
Neoplasms, Complex and Mixed
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins c-akt

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

United States

Source

Identifiers

PMID: 27454941
DOI: 10.1097/PAS.0000000000000707

Genes

BRAF
AKT1
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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