Article
Analysis of exposome and genetic variability suggests stress as a major contributor for development of pancreatic ductal adenocarcinoma.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Jun 2024
Peduzzi Giulia, Felici Alessio, Pellungrini Roberto, Giorgolo Francesca, Farinella Riccardo, Gentiluomo Manuel, Spinelli Andrea, Capurso Gabriele, Monreale Anna, Canzian Federico, Calderisi Marco, Campa Daniele
Abstract excerpt
BACKGROUND: The current knowledge on pancreatic ductal adenocarcinoma (PDAC) risk factors is limited and no study has comprehensively tested the exposome in combination with the genetic variability in relation to the disease susceptibility. AIM: The aim of this study was to analyze the exposome and its interaction with known genetic susceptibility loci, in relation to PDAC risk. METHODS: A case-control study...
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