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Article

Role of endocrine and genetic evaluation for infants with proximal hypospadias.

Journal of pediatric urology - 1 Oct 2025

Lee Victoria S, Finlayson Courtney, Hirsch Josephine, Yerkes Elizabeth B, Weisman Allison Goetsch, Leeth Elizabeth A, Cheng Earl Y, Johnson Emilie K

Abstract excerpt

PURPOSE: This study aims to determine if: (1) endocrine/genetic evaluation in infants with proximal hypospadias uncovers differences of sex development (DSD), and (2) phenotypic features or abnormal endocrine labs are associated with DSD. We further seek to update a proximal hypospadias testing algorithm that was proposed based on a prior study from our institution. MATERIALS AND METHODS: Infants <6 months of age...

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Algorithms
Disorders of Sex Development
Genetic Testing
Hypospadias
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Infant, Newborn

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PMID: 40348648
DOI: 10.1016/j.jpurol.2025.04.024

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