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Article

Evaluation of turnaround times and performance of in-house ChromaCode high-definition PCR compared to send-out next-generation sequencing in non-small cell lung cancer.

American journal of clinical pathology - 26 Aug 2025

Hogarth Nathan C, Al-Kawaaz Mustafa, Linder Mark W

Abstract excerpt

OBJECTIVE: Lung cancer is the leading cause of cancer deaths globally, with 1.8 million deaths annually. Advances in targeted therapy and molecular testing for key mutations in non-small cell lung cancer (NSCLC) have improved survival rates. The benchmark turnaround time for molecular testing is 10 days; however, send-out next-generation sequencing (NGS) can often take 14 to 28 days. METHODS: The ChromaCode NSCLC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40328657
DOI: 10.1093/ajcp/aqaf038

Genes

EGFR
KRAS
NTRK1
ROS1
ALK
BRAF
MET
RET

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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