An Improved Rapid and Sensitive Long Amplicon Method for Nanopore‐Based RSV Whole‐Genome Sequencing

Abstract excerpt

BACKGROUND: Whole-genome sequencing (WGS) provides critical insights into the respiratory syncytial virus (RSV) transmission and any emerging mutations that could impair the efficacy of monoclonal antibodies or vaccines that have been recently licenced for clinical use worldwide. However, the ability to sequence RSV genomes at large scale is limited by expensive and time-consuming sequencing methods. Oxford...

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