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Human adaptation response to obesity.

International journal of obesity (2005) - 1 Aug 2025

Jahanbani Alireza, Rezazadeh Davood, Sajadi Elham, Haj Hosseini Mahdiyeh, Ketabchi Deniz, EskandariRoozbahani Narges

Abstract excerpt

This article examines the human body's adaptive responses to obesity from biological, behavioral, and evolutionary perspectives. It explores how ancient survival mechanisms, such as fat storage during scarcity, have persisted but become maladaptive in modern contexts of food abundance and sedentary lifestyles. Using the Thrifty Gene Hypothesis and General Adaptation Syndrome (GAS), the study investigates how...

Topics

Humans
Obesity
Stress, Psychological
Adaptation, Physiological
Genetic Predisposition to Disease

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40287541
DOI: 10.1038/s41366-025-01791-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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