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Article

Causal association between endocrine diseases and lymphoid malignancies explored through two-sample Mendelian randomization analysis.

Scientific reports - 24 Apr 2025

Zhao Chenze, Zhang Yu, Qian Lili, Guo Qing, Zhu Ni

Abstract excerpt

Endocrine diseases are suspected contributors to lymphoid malignancies, but their precise association is unclear. This study aimed to investigate the causal relationship between various endocrine diseases-specifically type 2 diabetes, obesity, diabetic hypoglycemia, hyperlipidemia, and hyperthyroidism-and lymphoid malignancies, including lymphocytic leukemia and non-Hodgkin's lymphoma with subtypes like diffuse...

Read the complete abstract on PubMed

Topics

Humans
Mendelian Randomization Analysis
Endocrine System Diseases
Genome-Wide Association Study
Genetic Predisposition to Disease
Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Lymphoma

Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 40275078
DOI: 10.1038/s41598-025-99010-y
PMCID: PMC12022301

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