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LncRNA JINR1 regulates miR-216b-5p/ GRP78 and miR-1-3p/ DDX5 axis to promote JEV infection and cell death

24 Apr 2025

Abstract excerpt

ABSTRACT Japanese encephalitis virus (JEV) infection in the central nervous system (CNS) leads to neuroinflammation and neuronal cell death. Several long non-coding RNAs (lncRNAs) are differentially expressed during viral infection and regulate multiple aspects of viral pathogenesis. Previously, we have shown that JEV/West Nile virus (WNV) infection promotes JEV-induced non-coding RNA 1 ( JINR1 ) expression in...

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PMID: 40272157
DOI: 10.1128/jvi.00066-25

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