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Japanese encephalitis virus NS1 inhibits IFN-β production by interacting with DDX3X

15 Apr 2025

Abstract excerpt

Japanese encephalitis virus (JEV) is the causative agent of Japanese encephalitis, which poses great threats to the pig farming industry and human health. To establish infection, JEV has evolved sophisticated strategies to overcome the innate immune responses and finish its life cycle. Previous studies have shown that non-structural protein 1 (NS1) is closely related to its pathogenesis, while its molecular...

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PMID: 40231822
DOI: 10.1128/jvi.00077-25

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