Article
A universal point-of-care immunochromatographic test for the serodiagnosis of hepatitis D.
Journal of clinical microbiology - 14 May 2025
Lopes Thiciany Blener, Coelho Fabiana Fioravante, Roca Tárcio Peixoto, Oliveira Jéssica Karoline Augusta, Delagarde Valérian, Brichler Ségolène, Gómez Mendoza Diana Paola, Villalobos Salcedo Juan Miguel, Vieira Deusilene Souza, Le Gal Frédéric, Gazzinelli Ricardo Tostes, Fernandes Ana Paula
Abstract excerpt
Hepatitis D is estimated to affect 12 million people worldwide and is caused by the hepatitis D virus (HDV), a defective virus that requires the presence of the hepatitis B virus (HBV) for infection. Here, we report a new recombinant antigen (DTH10.1) to detect anti-HDV IgG antibodies, designed to include a consensus sequence of the HDV antigen, based on bioinformatic analysis of the eight HDV genotypes. Using...
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