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Article

Stage-specific phenotypic and transcriptional alterations in HaCaT keratinocytes exposed to acute and chronic blue light.

Photochemistry and photobiology - 1 Jan 2025

Tonolli Paulo Newton, Marie Suely Kazue Nagahashi, Oba-Shinjo Sueli Mieko, de Assis Leonardo Vinicius Monteiro, Baptista Maurício S

Abstract excerpt

Despite evidence that visible light (VL) has similar effects on human skin as those of UVA, VL is often viewed as harmless. High SPF sunscreen prevents erythema but can lead to overexposure to UVA and VL, with unknown consequences. To explore the impact of chronic blue light exposure, we irradiated (50 J/cm2, λ = 408 nm, three times a week) human immortalized keratinocytes under acute (3 irradiations),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40191980
DOI: 10.1111/php.14095

Genes

CENPX
EGR1
ELF3
FOSL1
KLF4
SRF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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