Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intratumoral Fusobacterium nucleatum is associated with better cancer-specific survival in head and neck cancer patients

1 Apr 2025

Abstract excerpt

Background The oral microbiome, particularly Fusobacterium nucleatum (Fn), has been implicated in head and neck cancers (HNC), influencing local immunity and Human Papillomavirus (HPV) status. Here, we evaluated the presence of Fn and its association with HPV infection, TERT promoter (TERTp) mutations, and patient outcomes.Materials and Methods We analyzed 94 formalin-fixed paraffin-embedded (FFPE) tumor tissues...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dysphagia Assessment and Management
Share to Head and Neck Cancer Studies
Share to Otolaryngology and Infectious Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40182114
DOI: 10.1080/20002297.2025.2487644

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intratumoral Fusobacterium nucleatum is associated with better cancer-specific survival in head and neck cancer patientsPMID 40182114Read ↗

Fusobacterium is toxic for head and neck squamous cell carcinoma and its presence may determine a better prognosisSemantic proximity Read ↗

Fusobacterium is enriched in oral cancer and promotes induction of programmed death-ligand 1 (PD-L1)Semantic proximity Read ↗

Comparative analysis of the tumor microbiome, molecular profiles, and immune cell abundances by HPV status in mucosal head and neck cancers and their impact on survivalSemantic proximity Read ↗

The Intersection between Oral Microbiota, Host Gene Methylation and Patient Outcomes in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

The Intratumor Bacterial and Fungal Microbiome Is Characterized by HPV, Smoking, and Alcohol Consumption in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

<i>Fusobacterium nucleatum</i> outer membrane vesicles activate the TNFR1/NF-κB signaling pathway to promote OSCC proliferationSemantic proximity Read ↗

Oral Microbiome as a Biomarker and Therapeutic Target in Head and Neck Cancer: Current Insights and Future DirectionsSemantic proximity Read ↗

Multi-Omics Integration Reveals the Crucial Role of Fusobacterium in the Inflammatory Immune Microenvironment in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Microbial And Molecular Differences According To The Location of Head And Neck CancersSemantic proximity Read ↗

A comprehensive analysis of intratumor microbiome in head and neck squamous cell carcinomaSemantic proximity Read ↗

Microbes translocation from oral cavity to nasopharyngeal carcinoma in patientsSemantic proximity Read ↗

Microbial and molecular differences according to the location of head and neck cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.