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Circadian clock is critical for fungal pathogenesis by regulating zinc starvation response and secondary metabolism

28 Mar 2025

Abstract excerpt

Circadian clocks are known to modulate host immune responses to pathogen infections, yet their role in influencing pathogen pathogenesis remains unclear. Here, we investigated the role of circadian clocks in regulating the pathogenesis of the fungal pathogen Fusarium oxysporum , which has multiple genes homologous to the Neurospora crassa frq due to gene duplication events, with Fofrq1 being the primary circadian...

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PMID: 40153515
DOI: 10.1126/sciadv.ads1341

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