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Molecular characterization and drug resistance pattern in pol gene of HIV-1 sub-subtypes circulating in Lahore, Pakistan.

Virus genes - 1 Jun 2025

Zubair Akmal, Zeb Adnan, Shahid Syed Ahsan, Javed Hasnain, Ali Muhammad

Abstract excerpt

This study aimed to determine sub-subtypes and circulating recombinant forms (CRFs) in Pakistan using the pol gene, identification of amino acid substitutions, structural changes, and drug resistance evaluation in the p66 region of reverse transcriptase. A total of 50 HIV-positive blood samples were collected from Lahore Pakistan, confirmed by Real Time-Polymerase Chain Reaction. The samples were further...

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PMID: 40146387
DOI: 10.1007/s11262-025-02149-z

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