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Article

Design of the First in Human Gene Therapy Trial of TLT-101 for Chronic Heart Failure (FIGHT-HF)

11 Feb 2025

Abstract excerpt

Design of the First in Human Gene Therapy Trial of TLT-101 for Chronic Heart Failure (FIGHT-HF) Heart failure (HF) is a major contributor to global morbidity and mortality, affecting millions worldwide and imposing a substantial economic burden on health care systems.Despite advancements in pharmacologic therapies, device development, and cardiac rehabilitation programs, HF prognosis remains suboptimal.Patients...

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PMID: 40139869
DOI: 10.1016/j.jacbts.2025.01.019

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