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Impact of media brand on cefiderocol disk diffusion results

25 Mar 2025

Abstract excerpt

ABSTRACT Cefiderocol is a siderophore cephalosporin that utilizes iron transport systems to cross cell membranes. This unique strategy complicates antimicrobial susceptibility testing (AST) due to variable iron content in media. While guidance for using iron-depleted media exists for broth microdilution (BMD), disk diffusion (DD) with commercial media is a common AST method in the clinical laboratory. We...

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PMID: 40130882
DOI: 10.1128/jcm.01648-24

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