[Germline mutations define the prognosis and therapy of pheochromocytomas and paragangliomas].

Abstract excerpt

Pheochromocytomas and paragangliomas are rare neuroendocrine tumors, where the genetic background is of particular importance in terms of the diagnosis, follow-up, treatment and prognosis of the disease. Although the prognosis in benign cases is encouraging, in the case of malignant disease the mortality rates are dramatically worse due to the high tumor burden and possible cardiovascular complications caused by...

Topics

• Humans
• Pheochromocytoma
• Paraganglioma
• Adrenal Gland Neoplasms
• Prognosis
• Germ-Line Mutation
• Proto-Oncogene Proteins c-ret