Graph-structured populations elucidate the role of deleterious mutations in long-term evolution.

Abstract excerpt

Birth-death models are used to understand the interplay of genetic drift and natural selection. While well-mixed populations remain unaffected by the order of birth and death and where selection acts, evolutionary outcomes in spatially structured populations are affected by these choices. We show that the choice of individual moving to vacant sites-parent or offspring-controls the initial mutant placement on a...

Topics

• Mutation
• Models, Genetic
• Selection, Genetic
• Genetic Drift
• Genetic Fitness
• Biological Evolution
• Genetics, Population