Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-Cell RNA Sequencing Reveals Peripheral Immune Cell Senescence and Inflammatory Phenotypes in Patients with Premature Ovarian Failure

1 Feb 2025

Abstract excerpt

Background: Premature Ovarian Failure (POF) is a heterogeneous syndrome characterized by ovarian dysfunction, frequently associated with autoimmune factors. The interaction between peripheral and ovarian immune signals remains unclear. Recent advancements in single-cell technology provide a unique opportunity to examine the complex peripheral immune response in POF patients at the microstructural level. This...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Reproductive Biology and Fertility
Share to Reproductive System and Pregnancy
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40026314
DOI: 10.2147/jir.s496130

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-Cell RNA Sequencing Reveals Peripheral Immune Cell Senescence and Inflammatory Phenotypes in Patients with Premature Ovarian FailurePMID 40026314Read ↗

Single-cell RNA sequencing of peripheral blood reveals immune cell dysfunction in premature ovarian insufficiencySemantic proximity Read ↗

Single-cell RNA sequencing reveals the follicle microenvironment of patients with premature ovarian insufficiencySemantic proximity Read ↗

Immune and oxidative stress disorder in ovulation-dysfunction women revealed by single-cell transcriptomeSemantic proximity Read ↗

Single-cell transcriptomic analysis of endometriosis provides insights into fibroblast fates and immune cell heterogeneitySemantic proximity Read ↗

Single‐Cell Atlas of Human Ovaries Reveals The Role Of The Pyroptotic Macrophage in Ovarian AgingSemantic proximity Read ↗

Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencingSemantic proximity Read ↗

A comprehensive cell profiling reveals new cell subtypes and immune dysfunction in peritoneal fluid of endometriosisSemantic proximity Read ↗

Single-cell analysis revealed that IL4I1 promoted ovarian cancer progressionSemantic proximity Read ↗

Identification of Key Genes and Potential New Biomarkers for Ovarian Aging: A Study Based on RNA-Sequencing DataSemantic proximity Read ↗

Integrated proteomics and scRNA-seq analyses of ovarian cancer reveal molecular subtype-associated cell landscapes and immunotherapy targetsSemantic proximity Read ↗

The role of immune cell signatures in the pathogenesis of ovarian-related diseases: a causal inference based on Mendelian randomizationSemantic proximity Read ↗

Whole-tissue deconvolution and scRNAseq analysis identify altered endometrial cellular compositions and functionality associated with endometriosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.