Astrocytomas IDH-mutant of posterior cranial fossa, clinical presentation, imaging features and onco-functional balance in surgical management.

doi:10.1007/s10143-025-03436-x

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Article

Astrocytomas IDH-mutant of posterior cranial fossa, clinical presentation, imaging features and onco-functional balance in surgical management.

Neurosurgical review - 27 Feb 2025

De Simone Matteo, Choucha Anis, Ranalli Carlotta, Pecoraro Giuseppina, Appay Romain, Chinot Oliver L, Dufour Henry, Iaconetta Giorgio

Abstract excerpt

IDH-mutant astrocytomas (AIDHmut) in the posterior cranial fossa (PCF) are rare and present substantial diagnostic and therapeutic challenges due to their location. We analyzed patients with PCF AIDHmut from our institutions, treated between December 2021 and September 2024. Additionally, we conducted a systematic literature review (from January 2021 to September 2024) using PubMed, Ovid MEDLINE, and Ovid EMBASE...

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PMID: 40014162
DOI: 10.1007/s10143-025-03436-x
PMCID: PMC11868189

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